Pregnenolone

April 9, 2024

In this episode of Scoliosis World, Dr Morningstar covers the effects of the cholesterol pathway and pregnenolone in patients with scoliosis.

  • Part of the cholesterol pathway
  • Every hormone in our body is made from cholesterol
  • Lowering cholesterol can be taken too far, to the point that a person cannot make hormones, leading to premature aging and neurodegenerative diseases
  • Your brain runs on cholesterol
  • Pregnenolone is one of the first byproducts of cholesterol metabolism
  • Cholesterol rises in the winter months
  • Pregnenolone converts into progesterone and DHEA; both important
  • Progesterone is implicated in scoliosis
  • Females with scoliosis have about half of the available progesterone that those without scoliosis have